Temperature-dependent cryoglobulin crystal transformation in peripheral blood

Cryoglobulin deposits on a blood smear.

A 61-year-old male presented with 2 months of bone pain. Complete blood count showed Hb 10 g/dL, white blood cell count 4.5 109/L, and platelets 130 109/L. The peripheral smear contained visible agglutinates and a blue background color (panel A). Aggregates of amorphous particles mimicking lysed cells were observed microscopically (panels C-E) with smaller and less stained deposits (panel E arr...

Temperature can prime human peripheral blood neutrophils in a p38MAPKalpha-dependent manner.

INTRODUCTION Previous ex vivo experiments by others suggest that elevated body temperature can prime the respiratory burst of human neutrophils. The mechanism of the priming phenomenon induced by temperature has not been addressed so far. Furthermore, the priming temperature range was not defined. MATERIAL/METHODS In the present study we explored ,under in vitro conditions, the influence of f...

Transformation of Lymphocytes in Cultures of Human Peripheral Blood.

Unusual morphological cryoglobulin manifestations on blood and bone marrow smears.

Case report A 66-year-old female presented with a 3 years history of multiple ulcerations on the lower extremities of both legs. The diagnosis of necrotic angiodermitis had been previously proposed. The skin lesions were numerous (6 on right side and 7 on left side), purpuric, evolutive and painful, with width ranging from 0.5 to 4.5 centimeters. No adenopathy, neither liver or spleen enlargeme...

Temperature Tunability of Dielectric/ Liquid Crystal / Dielectric Photonic Crystal Structures

Recently, photonic crystals doped with liquid crystal (LC) material havegained much research interest. In this article new ternary one-dimensional photoniccrystal introduced and studied. The liquid crystal layer of 5CB and 5PCH is sandwichedby two dielectric layers. For the first time, we use four structures SiO2/UCF35/CaF2,SiO2/5CB/CaF2, NFK51/UCF35/NPSK53 and NFK51/5CB/NPSK53. The effect ofte...